Biomedical and Translational Informatics Laboratory

Publications - 2018

  • Volpi S, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Rodriguez LL, Aronson S, Cavallari LH, Denny JC, Dressler LG, Johnson JA, Klein TE, Leeder JS, Piquette-Miller M, Perera M, Rasmussen-Torvik LJ, Rehm HL, Ritchie MD, Skaar TC, Wagle N, Weinshilboum R, Weitzel KW, Wildin R, Wilson J, Manolio TA, Relling MV. Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects. Clin Pharmacol Ther. 2018 Feb 20. doi: 10.1002/cpt.1048. PMID:29460415. 
  • Nielsen JB, Fritsche LG, Zhou W, Teslovich TM, Holmen OL, Gustafsson S, Gabrielsen ME, Schmidt EM, Beaumont R, Wolford BN, Lin M, Brummett CM, Preuss MH, Refsgaard L, Bottinger EP, Graham SE, Surakka I, Chu Y, Skogholt AH, Dalen H, Boyle AP, Oral H, Herron TJ, Kitzman J, Jalife J, Svendsen JH, Olesen MS, Njølstad I, Løchen ML, Baras A, Gottesman O, Marcketta A, O'Dushlaine C, Ritchie MD, Wilsgaard T, Loos RJF, Frayling TM, Boehnke M, Ingelsson E, Carey DJ, Dewey FE, Kang HM, Abecasis GR, Hveem K, Willer CJ. Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. Am J Hum Genet. 2018 Jan 4;102(1):103-115. PMID: 29290336
  • Li B, Verma SS, Veturi YC, Verma A, Bradford Y, Haas DW, Ritchie MD. Evaluation of PrediXcan for prioritizing GWAS associations and predicting gene expression. Pac Symp Biocomput. 2018;23:448-459. PMID: 29218904. PMCID: PMC5749400
  • Veturi Y, Ritchie MD. How powerful are summary-based methods for identifying expression-trait associations under different genetic architectures? Pac Symp Biocomput. 2018; 23:228-239. PMID: 29218884. PMCID: PMC5785784
  • Verma A, Bradford Y, Dudek SM, Verma SS, Pendergrass SA, Ritchie MD. A simulation study investigating power of Phenome-Wide Association Studies. BMC Bioinformatics, 2018 Apr 4;19(1):120. doi: 10.1186/s12859-018-2135-0. PMID:29618318
  • Verma SS, Josyula N, Verma A, Zhang X, Veturi Y, Dewey FE, Hartzel DN, Lavage DR, Leader J, Ritchie MD, Pendergrass SA. Rare variants in drug target genes contributing to complex diseases, phenome-wide. Sci Rep. 2018 Mar 15;8(1):4624. doi: 10.1038/s41598-018-22834-4. PMID:29545597; PMCID:PMC5854600
  • Verma A, Lucas A, Verma SS, Zhang Y, Josyula N, Khan A, Hartzel DN, Lavage DR, Leader J, Ritchie MD, Pendergrass SA. PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger. Am J Hum Genet. 2018 Mar 19. pii: S0002-9297(18)30062-4. doi: 10.1016/j.ajhg.2018.02.017. PMID:29606303
  • Basile AO, Ritchie MD. Informatics and machine learning to define the phenotype.  Expert Rev Mol Diagn. 2018 Mar;18(3):219-226. doi: 10.1080/14737159.2018.1439380. Epub 2018 Feb 16. PMID:29431517
  • Verma SS, Ritchie MD. Another Round of "Clue" to Uncover the Mystery of Complex Traits. Genes (Basel). 2018 Jan 25;9(2). pii: E61. PMID: 29370075